个人简介

任江，博士毕业于莱顿大学医学中心。目前任南昌大学生物医学创新研究院，特聘研究员。

研究方向

蛋白质翻译后修饰对信号通路的影响，及其所具有的生理、病理作用研究，主要包括先天性免疫调节、肿瘤的发生发展。

代表性论文

1.Ren J, Liu S, Zhang L. Inhibitor of differentiation 3 confers the robust anti-tumor activity of Kupffer cells. MedComm 2024, 5(9):e708.

2.Ren J#, Wang S#, Zong #Z, Pan T#, Liu S, Mao W, Huang H, Yan X, Yang B, He X*, Zhou F*, Zhang L*. TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence. Nature Communications 2024, 15(1):244.

3.Ren J#, Yu P#, Liu S#, Li R, Niu X, Chen Y, Zhang Z, Zhou F, Zhang L: Deubiquitylating Enzymes in Cancer and Immunity. Advanced Science 2023:e2303807.

4.Ren J#, Zhang Z#, Zong Z, Zhang L, Zhou F: Emerging Implications of Phase Separation in Cancer. Advanced Science 2022:e2202855.

5.Zong Z#, Wei Y#, Ren J#, Zhang L, Zhou F: The intersection of COVID-19 and cancer: signaling pathways and treatment implications. Molecular Cancer 2021, 20:76.

6.Ren J, Wang Y, Ware T, Iaria J, Ten Dijke P, Zhu HJ: Reactivation of BMP signaling by suboptimal concentrations of MEK inhibitor and FK506 reduces organ-specific breast cancer metastasis. Cancer Letters 2020, 493:41-54.

7.Ren J, Smid M, Iaria J, Salvatori DCF, van Dam H, Zhu HJ, Martens JWM, Ten Dijke P: Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression. Breast Cancer Research 2019, 21:109.

8.Sow HS#, Ren J#, Camps M, Ossendorp F, Ten Dijke P: Combined Inhibition of TGF-β Signaling and the PD-L1 Immune Checkpoint Is Differentially Effective in Tumor Models. Cells 2019, 8.

9.Liu S, Ren J, Ten Dijke P: Targeting TGFβ signal transduction for cancer therapy. Signal Transduction and Targeted Therapy 2021, 6:8.

10.Barone M, Müller M, Chiha S, Ren J, Albat D, Soicke A, Dohmen S, Klein M, Bruns J, van Dinther M, et al: Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells. PNAS 2020, 117:29684-29690.

11.Sundqvist A, Morikawa M, Ren J, Vasilaki E, Kawasaki N, Kobayashi M, Koinuma D, Aburatani H, Miyazono K, Heldin CH, et al: JUNB governs a feed-forward network of TGFβ signaling that aggravates breast cancer invasion. Nucleic Acids Research 2018, 46:1180-1195.

主持项目

1. 国家自然科学基金（地区），主持，2025.01-2028.12。