教育教学

黄春洪

2026-01-01

黄春洪,教授,博士生导师。现任南昌大学创新创业学院院长(教务处副处长兼)。2006年博士毕业于中国药科大学,2014-2015年在波士顿大学公派留学。现为创新创业学院院长兼教务处副处长。江西省级高层次人才,中青年骨干教师。担任JoVE review editor,同时为IJMS、toxins、 Biochimie、Biomedicine & pharmacotherapy、animals、 Toxicon、《生物化学与分子生物学报》等杂志审稿专家。

主要从事《生物化学与分子生物学》、《生物信息学》、《生物软件》等本科与研究生教学;曾获中国宝钢优秀教师,江西省高水平本科教学团队、南昌大学教学名师工作室、十大教学标兵,主持国家一流课程一门,省级课程2门,编写101教材《生物化学》、人卫版《生物化学与分子生物学(第10版)》、《生物化学》云教材,主编《医学生物化学与分子生物学实验指南》并获江西省规划教材。指导学生在大学生创新大赛、挑战杯、医学创新大赛(基础医学论坛)获得国家级金奖、银奖等10余项。获创新创业优秀导师,挑战杯全国优秀导师,园丁奖,宝钢教育奖,教学名师等荣誉称号。

详见南昌大学教师个人主页https://teacher.ncu.edu.cn/publish/070779/

教育经历:

[1] 200309-200606 中国药科大学 博士研究生

[2] 200009-200306 江苏省中科院研究所 硕士研究生

[3] 199609-200006 南昌大学 大学本科

工作履历:

[1] 2014.1-今 生物化学 教授 南昌大学

[2] 2006年7月-2013年12月 生物化学与分子生物学教师 南昌大学

科研项目:

蛇毒生产质量标准的方法研究

多功能PLIγ分子改组与淘筛及广谱抗蛇毒PLA2机制研究

多功能高效PLIγ基因改组和抗蛇毒活性评价

抗蛇毒蛋白PLIγ的分子改造及模拟肽设计

蛇血清PLI-γ对sPLA2炎症通路的干预作用及相关机制研究

基于2DE-western blot技术筛选蛇毒毒素组C型凝集素蛋白新组分

黄春洪杰出青年人才资助计划项目

广谱型抗蛇毒蛋白质药物的基因表达与药效研究

华游蛇血清sPLA2抑制剂干预人炎症通路的研究

华游蛇肝脏“抗蛇毒组”解析及抗毒机制研究

华游蛇PLIγ抗蛇毒局部和系统肌肉毒活性及机制研究

科研成果:

主持国家自然基金5项,江西省杰出青年人才项目、江西省自然科学基金重点项目等10项,发表Sci论文40余篇。

近期代表性论文

1. Jianqi Zhao, Linfeng Wang, Xiao Shi, Yang yang, Chunhong Huang. Toxicological Profiling of Venoms from Ten Major Chinese Snakes: A Mass Spectrometry-Based Proteomic and Multiroute Assessment. Archives of toxicology. 2025.

2. Jiahao Liu, Linfeng Wang , Mengxia Xie , Wenjie Zhao , Jiaqi Sun , Yuji Jin , Meiling Liu , Jianqi Zhao , Lixia Cheng , Cheng Wen , Xiaowen Bi, Chunhong Huang. Varespladib attenuates Naja atra-induced acute liver injury via reversing Nrf2 signaling mediated ferroptosis and mitochondrial dysfunction, Redox Report. 2025, 30:1, 2507557

3. Jianqi Zhao, Guangyao Liu, Xiao Shi, Yang Yang, Chunhong Huang. Combination of Rhamnetinand RXP03 Mitigates Venom-InducedToxicity in Murine Models: Preclinical Insights into Dual-Target AntivenomTherapy. Toxins 2025, 17, 280

4. Jianqi Zhao , Xiao Shi, Guangyao Liu, Yang Yang, Chunhong Huang. Geographic Variation in Venom Proteome and Toxicity Profiles of Chinese Naja atra: Implications for Antivenom Optimization. Toxins, 2025, 17, 404;

5. Qi Lian, Denghong Zhang, Kepu Fu, Chunju Liu, Liyun Cao, Kejia Xiong, Chunhong Huang. The molecular basis of venom resistance in the non-venomous snake Sinonatrix annularis. Journal of Chromatography B. 2022,1195:123182.

6. Qi Lian, Lipeng Zhong, Kepu Fu, Yuxin Ji, Xiangyue Zhang, Chunju Liu, Chunhong Huang. Hepatic inhibitors expression profiling of venom-challenged Sinonatrix annularis and antidotal activities. Biomedicine & Pharmacotherapy. 2022, 156, 113900.

7. Kepu Fu, Jianqi Zhao, Lipeng Zhong, Haiyan Xu, Xinhui Yu, Xiaowen Bi, Chunhong Huang. Dual therapy with phospholipase and metalloproteinase inhibitors from Sinonatrix annularis alleviated acute kidney and liver injury caused by multiple snake venoms. Biomedicine & Pharmacotherapy. 2024, 177, 116967.

8. Kepu Fu, Liyun Cao, Yitao Tang, Jianqi Zhao, Kejia Xiong, Congjiang Hong, Chunhong Huang. The anti-myotoxic effects and mechanisms of Sinonatrix annularis serum and a novel plasma metalloproteinase inhibitor towards Deinagkistrodon acutus envenomation. Toxicology letters, 2023, 388, 13.

9. Wenjie Zhao, Jiahao Liu, Sidan Wang, Qinqin Tao, Qiongqiong Lei, Chunhong Huang. Varespladib mitigates acute liver injury via suppression of excessive mitophagy on Naja atra envenomed mice by inhibiting PLA2. Toxicon. 2024, 242, 107694.

10.Sidan Wang , Haotian Fu , Zheng Xu , Chunhong Huang. The Interaction Between Microbiota and Stem Cells on Progression of Osteoarthritis and Engineered Stem Cell for Enhancing Osteoarthritis Treatment. International Journal of Nanomedicine. 2025:20 3219-3234.

11. Wei Wu, Wen-Xuan Li, Chunhong Huang. Phospholipase A2, a nonnegligible enzyme superfamily in gastrointestinal diseases. Biochimie. 2022, 194, 79.

12. Xiaowen Bi, Miao Zhang , Jinyi Zhou, Xintong Yan, Lixia Cheng, Lan Luo, Chunhong Huang, Zhimin Yin. Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc. Cellular signalling. 2023,112:110913.

13. Peiyi Luo, Yuxin Ji, Xiaohan Liu, Weiyun Zhang, Ruoxi Cheng, Shuxian Zhang, Xiao Qian, Chunhong Huang. Affected inflammation-related signaling pathways in snake envenomation: A recent insight. Toxicon, 2023, 234, 107288.

14. Jiaqi Sun, Jiahao Liu, Meiling Liu, Xiaowen Bi, Chunhong Huang. New perspective for pathomechanism and clinical applications of animal toxins: Programmed cell death. Toxicon, 2024, 249, 108071.