中文

王小磊

王小磊 博士

南昌大学化学化工学院教授

际銮书院院长

研究方向:生物医用纳米技术,3D打印,靶向药物载体设计,环境分析,生物分析

教育工作经历

受教育经历

2006/09-2009/12,长春应用化学研究所,电分析化学国家重点实验室,博士导师杨秀荣教授

2003/09-2006/06,南昌大学,化学系分析化学专业,硕士导师倪永年教授

1999/09-2003/06,南昌大学,化学系,学士指导老师 曾晓平

研究工作经历

2019/11-至今,南昌大学,发改委生物工程药物及其技术国家地方联合中心 副主任

2019/04-至今,南昌大学,化学学院副院长

2013/12-至今,南昌大学,转化医学研究院,研究员,院长助理20091122012/12,长春应用化学研究所,电分析化学国家重点实验室,助理研究员

教学简介

全国大学生创新创业大赛总决赛优秀奖指导老师(董丽娜,余芬);

南昌大学化学系201420152016年本科优秀毕业论文指导老师(余芬、宋相、余涛);

南昌大学第十五届挑战杯大学生课外学术科技作品竞赛特等奖指导老师(胡淇芃);

南昌大学研究生高水平科研成果奖指导老师(史晓彤、薛超文、刘苗星),第十一届全国大学生药苑论坛创新成果奖三等奖指导老师(刘廷武);

第二届江西省创新创业学术交流活动药学学科分论坛本科生组一等奖指导老师(刘廷武);

2018年浩瀚杯创青春江西省大学生创业大赛创业计划竞赛金奖指导老师(陈敬煌);

第十六届挑战杯南昌大学大学生课外学术科技作品竞赛省级特等奖,国家级铜奖指导老师(刘宽);

第五届互联网+”创新创业大赛高教赛道创意组省级金奖,国家级银奖指导老师(吕中盛)

科研项目

1 纳米磁力印刷技术的开发及其在智能生物材料领域的应用

2 纳米修饰与3D打印联用技术在医用材料中的应用

3 多孔氧化锌材料的快速制备与生物医学应用研究

4 曲面纳米修饰结合3D打印技术在生物医用材料领域的应用

5 利用3D打印技术构筑具有智能药物控释能力的仿生植入体系

6 南昌市新医用材料研究创新团队

7 江西省“5511”优势科技创新团队

8 双效抗炎医用导管的研发

社会兼职

国家科技奖励答辩会评专家(化学组)

科技部重大专项会评专家(生物医用材料方向)

中国青年科协委员、中国卫生部抗菌协会委员

江西省外国专家引进评审专家

江西省研究型医院学会骨科分会基础研究组组长

广东省重大科技项目评审专家(生物医用材料方向)

获奖情况

1.王小磊、杨秀荣、朱慧,微生物与功能纳米阵列的交叉应用,吉林省科协/吉林省人事厅,吉林省自然科学学术成 果奖,一等奖,20122.杨秀荣、逯乐资医用导管的慧、艾可龙,王伟东,生物分子识别与相互作用的分析化学基础研究,吉林省科技厅,吉林省科技进步奖,一等奖,2012

3.辛洪波、王小磊、洪葵、王建斌、邓柯玉、符民桂、罗时文、何明 中国侨联贡献奖(创新团队)20144.王小磊、辛洪波、朱慧,微生物与纳米技术的交叉应用,江西省科学技术奖自然科学奖,二等奖,2016

5.王小磊 中科院电分析化学国家重点实验室青年论坛杰出报告奖,2016

6.王小磊、胡淇芃,南昌大学第十五届挑战杯大学生课外学术科技作品竞赛,特等奖,20177.王小磊、郭光华、陈敬煌、王文燕、董丽娜、朱、王家福、张楚汐, 浩瀚杯创青春江西省大学生创业大赛创业计划竞赛,金

奖,2018

8.王小磊、艾凡荣、刘廷武,基于3D打印的伤口原位冷却与快速止血系统, 第十一届全国大学生药苑论坛创新成果奖,三等奖2018

9.王小磊、全国再生医学材料大会青年论文奖,2018

10.王小磊、陈敬煌、董丽娜,中国创新创业大赛国际第三代半导体专业赛东南赛区,省级三等奖,2018

11.王小磊、廖岚、刘宽、吕中盛,第十六届挑战杯南昌大学大学生课外学术科技作品竞赛,省级特等奖,国家级铜奖,201912.王小磊、廖岚、吕中盛、刘宽,江西省第五届互联网+”创新创业大赛高教赛道创意组,省级金奖,国家级银奖,2019

13.王小磊,“新时代貉鄱先锋突出贡献好榜样荣誉称号,2019

14.王小磊,江苏省双创人才企业创新类荣誉称号,2019

15.王小磊,被授予中国高校创新创业先进事迹获得者荣誉称号,2019

代表性论文及专利

1、期刊论文(仅列二区以上高影响因子的部分期刊):

1. Liguo Jin, Ping Hu, Yinyin Wang, Luojia Wu, Kang Qin, Haoxin Cheng, Shuhua Wang, Bingxing Pan, Hongbo Xin, WenhuaZhang*, Xiaolei Wang*. Black Phosphorus Assisted Depression Therapy with Fast-Acting and Low Toxic Properties, AdvancedMaterials,2020,32 (2),e1906050.(影响因子25.809-)

2. Xiaolei Wang, Hui Zhu, Fan Yang, and Xiurong Yang*, Biofilm Engineered Nanostructures, Advanced Materials, 2009, 212815-2818.(影响因子25.809-)

3. Xiaolei Wang, Chaochao Wei, Mengke Liu, Ting Yang, Weimin Zhou, Ying Liu, Kui Hong, Shuhua Wang and Xingwei Ding*Near-infrared Triggered uPA Released Nanospheres for Localized Hyperthermia Enhanced Thrombolysis, Advanced FunctionalMaterials, 2017,27 (40),1701824.(影响因子15.621-)

4. Xiaolei Wang, Hui Zhu, Yi Bao, Fan Yang, and Xiurong Yang*, Uniform Hierarchical Frameworks Patterned by MovableMagnetic Microparticles, ACS Nano,2011,5,3250-3256.(影响因子13.903-)

5. Weiwei Bao, Lin Xie, Xuhui Zeng, Hang Kang, shigi Wen, Ben cui, Wenting Li, Yisong Qian, Jie Wu, Ting Li, Keyu DengHongbo Xin, Xiaolei Wang*.Cocktail-lnspired Mledium Term Male Birth Control Strategy with Physical/Chemical DualContraceptive Effects and NlR Remote Self-Cleared Properties, ACs Nano,2019, 13(2), 1003-1011.(影响因子13.903,-)

6. Xingwei Ding, Can Hong, Guoliang Zhang, jiagi liu, Huan Ouyang, Mlanyu Wang, Lina Dong, Wei Zhang, Hongbo Xin, XiaoleiWang*. Champagne inspired dual chained-responsive thrombolytic drug release platform for accelerated thrombolysis,Nanoscale Horizons, 2019,4(6),1277-1285.(影响因子9.095-)

7. Xiaotong Shi, Chaowen Xue, Fang Fang, Xiangwei Song, Fen Yu, Miaoxing Liu, Zhipeng Wei, Xuan Fang, Dongxu Zhao,Hongbo Xin*, and Xiaolei Wang*, Full Spectrum Visible LED Light Activated Antilbacterial System Realized by Optimized CuzOCrystals, ACS Applied Materials &Interfaces, 2016,8 (13),8386-8392.(影响因子8.456,一区)

8. Chaowen Xue, Xiaotong Shi, Xuan Fang, Haiyan Tao, Hui Zhu, Fen Yu, Xingwei Ding, Miaoxing Liu, Fang Fang, Fan YangZhipeng Wei, Tingtao Chen, Zongliang Wang, Guoping Wang, Xigao Cheng, Junchao Wei, Yingjie Lin, Keyu Deng, XiaoleiWang*, and Hongbo Xin*., The "Pure Marriage” between 3D Printing and Well-Ordered Nanoarrays by Using PEALD AssistedHydrothermal Surface Engineering, Acs Applied Materials &Interfaces,2016,8 (13),8393-8400.(影响因子8.456,-)

9. Hang Liao, Xinxin Miu, Jing Ye, Tianlong Wu, Zhongbo Deng, Chen Li, jingyu Jia, Xigao Cheng* and Xiaolei Wang*. fallingLeaves inspired ZnO Nanorods-Nanoslices Hierarchical Structure for lmplant Surface Modification with Two Stage ReleasingFeatures, ACS Applied Materials & Interfaces, 2017,9 (15)13009-13015.(影响因子8.456,-)

10. Lina Dong, Xiao Liu, Tian Wang, Bixing Fang, jinghuang Chen,Chen Li, Xinxin Miao, Chaochao Wei, Fen Yu, Hongbo Xin, KuiHong *, Xingwei Ding*, Xiaolei Wang*, Localized light-Au-hyperthermia treatment for precise, rapid and drug-free blood clotlysis, ACS Applied Materials & Interfaces, 2019, 11(2),1951-1956.(影响因子8.456-)

11. Fen Yu, Xiao Cui, Yuanyuan Lang, Fei Huang, lingfang Wang, Xinxin Miao, Fanrong Ai, Caifeng Xie, Hongbo Xin, Chen Yangand Xiaolei Wang*, Real Time Manipulation of lntestinal Peristalsis by Enteric Encapsulated Mlagnetic Nano-particles &Wearable 3D-Printed Devices, NPG Asia materials, 2019, 11(1),33.(影响因子8.052,-)

12. Haichuan Peng, Chuxi Zhang, Manyu Wang, Wei Zhang, Bin Xu, Xiaoxiao Yan, Hongbo Xin, Xiaolei Wang*, Blackphosphorus modified soluble microneedle patch for painless, effective and accurate body slimming, Applied Materials Today,2020.DO1:(影响因子8.023)10.1016/i.apmt.2020.

13. Xiaolei Wang, Hui Zhu, Jia Zhang, Xuexia Liu, Fan Yang, Xiurong Yang*. Selected Region Functionalized Fungi with MagneticTargeting Properties and Versatile Purification Capabilities, Nanoscale, 2012,4,3629-3634.(影响因子6.97,-)

14. Miaoxing Liu, Sizhen Su, Yimin Li, Xiangwei Song, Fen Yu, Xingwei Ding, Hongbo Xin and Xiaolei Wang*, Air Flow AssistedOne Step Synthesis of Porous Carbon with Selected Area Enriched Ag/ZnO Nanocomposites, ACs Sustainable Chemistry &Engineering,2017.5,5651-5656.(影响因子6.97-)

I5. Fengshun Li, Miaoxing Liu, Xiangwei Song, Chaowen Xue, Fanrong Ai, Chen Li, HongBo Xin, Xiaolei Wang*. Diet CultureInspired Facile Nano-engineering. Acs sustainable Chemistry & Engineering,2017,5(9),7979-7984.(影响因子6.97,-)

1 6. Xiaolei Wang, Fan Yang, Wen Yang, Xiurong Yang*, A Study on the Antibacterial Activity of One-dimensional ZnO NanowireArrays: Efects of the Orientation and Plane Surface, Chemical Communications, 2007,43, 4419-4421.(影响因子6.164,-)

17.Ting Li, Fang Fang Yang, Yu shen, Wan ji, Weiwei Bao, Tianran Zhang, Ai fanrong, Xingwei Ding, Hongbo Xin, Xiaolei WangSurface nano-engineered wheat straw for portable and adjustable water purification, Science of the Total Environment, 2018,655,1028-1036.(影响因子5.589,二区)

18. Fei Cao, Bin Zeng, Yanglong Zhu, Fen Yu, Mlanyu Wang, Xiangwei Song, Xinyan Cheng, liming Chen and Xiaolei Wang*.Porous ZnO Modified Silk Suture with Dual light Defined Antibacterial, Healing Promotion and Controlled self-degradationCapabilities, Biomaterials Science,2019,8 (1),250-255.(影响因子5.251,二区)

19. Lina Dong, Wenyan Wang, jinghuang Chen, Xingwei Ding, Bixing Fang, Xinxin Miao, Yu Liu, Fen Yy, Hongbo Xin and XiaoleiWang*, Siliver nanowire net knitted anisotropic aerogel as an ultralight and sensitive physiological activity monitor, BiomaterialsScience.2018,6(9),2312-2315.(影响因子5.251,二区)

20. Wei Zhang, jinzhu Hu, Yan Zhou, Yutong Chen, Fen Yu, Can Hong, Liming Chen, Hongbo Xin, Kui Hong* and Xiaolei Wang*Latex and a ZnO-based multi-functional material for cardiac implant-related inflammation, Biomaterials Science, 2019, 7. 41 84

4196.(影响因子 5.251,二区)

21. Mengwei Xiao, Zhaohua Shen, Weiwei Luo, Bei Tan, Xiangrui Meng, Xing Wu, Shuai Wu, Kai Nie, Ting Tong, junbo Hong,Xiaolei Wang* and Xiaoyan Wang*, new colitis therapy strategy via the targetcolonization of magnetic nanoparticleinternalizedRoseburia intestinalis, Biomaterials Science,2019,7(10),4174-4185.(影响因子5.251,二区)

22. Feng Zhang, Weiwei Bao, Ruirui Li, Siyu Zhao, Yuxiao Liu, Yingying Xu, Lan Liao* and Xiaolei Wang*, Microneedlescombined with sticky and heatable hydrogel for local painless anesthesia, Biomaterials Science, 2019,7(11),4503-4507.(影响因子5.251,二区)

23. jing Ye, Jianjan Deng, Yutong Chen, Ting Yang, Yanglong Zhu, Chongxue Wu, Tianlong Wu, jingyu Jia, Xigao Cheng* andXiaolei Wang*, Cicada and catkin inspired dual biomimetic antibacterial structure for the surface modification of implantmaterial, Biomaterials Science,2019,7,2826-2832.(影响因子5.251,二区)

24. Xiaolei Wang, Hui Zhu, Wen Yang, Fan Yang, Xiurong Yang*, Rapid and Tunable Patterning of ZnO Nanoarrays withoutTemplate or Catalyst, Chemistry -A European Journal, 2009,15,4253-4257.(影响因子5.160,二区)

25. Xiaolei Wang, Hui Zhu, Zhongjun Wang, fan Yang, Xiurong Yang*, Spontaneously Pattemned ZnO Nanoarrays, Chemistry - AEuropean Journal,2009,15,11473-11477.(影响因子5.160,二区)

26. Fen Yu, Xuan Fang, Huimin jia, Miaoxing Liu, Xiaotong shi, Chaowen Xue, Tingtao Chen, Zhipeng Wei, fang fang, Hui Zhu,ling Feng, Xiaolei Wang*. “Zn” or "O" ? The first 3D Printing Assisted Study for the Atomic Level Comparison onAntibacterial Studies, Chemistry-A European Joumal, 2016,22(24),8053-8058.(影响因子5.160,二区)

26. Fen Yu, Xuan Fang, Huimin jia, Miaoxing Liu, Xiaotong Shi, Chaowen Xue, Tingtao Chen, Zhipeng Wei, Fang fang, Hui Zhu,Jing Feng, Xiaolei Wang*. “Zn” or “0” ? The first 3D Printing Assisted Study for the Atomic Level Comparison onAntibacterial Studies, Chemistry-A European Journal, 2016,22(24),8053-8058.(影响因子5.160,二区)

27. Xiaolei Wang, Hui Zhu, Xuexia liu and Xiurong Yang*, Artificial Magnetotactic Probiotics for In Vivo Targeting Therapy.Journal of Materials Chemistry B, 2013,1,1573-1578.(影响因子5.047,二区)

28. Miaoxing Liu, Fang Fang, Xiangwei Song, Fen Yu, Fengshun Li, Xiaotong Shi, Chaowen Xue, Tingtao Chen and XiaoleiWang*.The first Visually Observable Three-mode Antibiotic Switch and its Relative 3D Printing Assisted Applications, Journalof Materials Chemistry B,2016,4,2544-2547.(影响因子5.047,二区)

29. Chaowen Xue, Xiangwei Song, Mingzhuo Liu, Fanrong Ai, Miaoxing Liu, Qiannan Shang, Xiaotong Shi, Fengshun Li, XiaoyiHe, Lin Xie, Tingtao Chen, Hongbo Xin, Xiaolei Wang*. A High-efficient, Low Toxic and Wide-spectrum Antibacterial CoatingDesigned for 3D Printed lmplants with Tailorable Releasing Properties, journal of Materials Chemistry B, 2017, 5, 4128-4136.(影响因子5.047,二区)

30. Lina Dong, Chunzhuo Liu, Fen Yu, Xingwei Ding, Ting Li, Qipeng Hu, Miaoxing Liu, fang Fang, Hongbo Xin and XiaoleiWang*. Natural Extracted Aerogels with inherent Anisotropy and their 3D Printing Assisted Biomedical Applications, Journal ofMaterials Chemistry B,2017,5,6217-6220.(影响因子5.047,二区)

31. fanrong Ai, Tingwu Liu, Yu liu, Kang Yang, Yishen Liu, Wenyan Wang, Fushan Yuan, lina Dong, Hongbo Xin* and XiaoleiWang*, A 3D printed wound cooling system incorporated with iniectable, adsorbable, swellable and broad spectrumantibacterial scaffolds for rapid hematischesis processing, Journal of Materials Chemistry B, 2018,6,5940-5948.(影响因子5.047,二区)

32. Huan Ouyang, Zhuli Zheng, Yutong Chen, Yu Liu, Can Hong, Yanglong Zhu,lianiian Deng, Xingwei Ding, Weimin Zhou* and Xiaolei Wang*. A Magnetically Modified Black Phosphorus Nanosheets-basedHeparin Delivery Platform for Preventing DVT Accurately, Journal of Materials chemistry B, 2019,7, 6099-6108.(影响因子5.047,二区)

33. Mingzhuo Liu, Huiging Zhang, Dinghong Min, XinXin Miao, Fengshun Li, Lina Dong, Juanjuan Xing, Guanghua Guo*, FeiGuo, Xiaolei Wang*, Dual layered wound dressing with simultaneous temperature & antibacterial regulation properties,Materials Science and Engineering C, 2018, 93(1),873-879.(影响因子4.959,二区)

34. liming Chen, Cuicui Zhang, Jiani Xiao, jie You, Wei Zhang, Yu Liu, Liang Xu, Anwen Liu, Hongbo Xin, Xiaolei Wang*. Localextraction and detection of early stage breast cancers through a microneedle an nano-Ag/MBL film based painless and blood.free strategy, Materials Science & Engineering C, 2020,109,110402.(影响因子4.959,二区)

35. Chen Li, fanrong Ai, Xinxin Miao, Hang Liao, Fengshun Li, Mingzhuo Liu, Fen Yu, Lina Dong, Ting Li, Xiaolei Wang*. Thereturn of ceramic implants"": Rose stem inspired dual layered modification of ceramic scaffolds with improved mechanical andanti-infective properties, Materials Science & Engineeringc,2018, 93,873-879.(影响因子4.959,二区)

36. Xiaheng Wang, Houyou Fan, Feng Zhang, Siyu Zhao, Yuxiao liu, Yingying Xu, Runfa Wu, Dongfang Li, Yang Yang, Lan Liao,Hongshui Zhu*, Xiaolei Wang*, Antibacterial Properties of Bilaver Biomimetic Nano-ZnO for Dental implants, ACs BiomaterialsScience & Engineering,2020,6,1880-1886,(影响因子4.511.区銻霓视聂懂脚優)

37. Miao Xinxin, Liao Hang, Deng Zhongbo, Li Chen, Wu Tianlong, Zhang Huiging, Liu Miaoxing, Cheng Xigao, Wang Xiaolei*."Dandelion" inspired Dual-Layered Nanoarays with Two Model Releasing Features for the Surface Modification of 3DPrinting Implants, ACS Biomaterials-Science & Engineering, 2017,3,2259-2266.(影响因子4.511,二区)

38. Ting Li, Fanrong Ai, Wanji Shen, Yu Yang, Yan Zhou, Jianjian Deng, Chen Li, Xinwei Ding, Hongbo Xin, Xiaolei Wang*.Microstructural Orientation and Precise Regeneration: A Proof-of-Concept Study on the Sugar-Cane-Derived lmplants withBoneMimetic Hierarchical Structure, ACs Biomaterials Science & Engineering, 2018, 4(12),4331-4337.(影响因子4.511,二区)

39. Feng Zhang, Chongxue Wu, Ziyu Zhou, jiaolong Wang, Weiwei Bao, Lina Dong, Zihao Zhang, jing Ye, Lan Liao* and XiaoleiWang* .Blue-light -Activated Nano-Ti02@PDA for Highly Efective and Nondestructive Tooth Whitening, ACs Biomaterials-Science & Engineering,2018,4(8),3072-3077.(影响因子4.511,二区)

40.yu Liu, Chaochao Wei, Long Huang, Weizhu Liu, jiagi lin, Leifeng Chen, Yalan Yang, Ping Hu*, Anwen Liu*, and XiaoleiWang*, Loquat inspired Janus drug delivery system for flexible and robust tumor targeting therapy, ACs Biomaterials science &Engineering,2019,5(2),740-747.(影响因子4.511,二区)

41. Ruolei Li, Fei Cao, Yutong Chen, Peixin Zhang, Chunhong Huang, Hongbo Xin, Jun Wang*, Xiaolei Wang*. A MOF &hydrogel based strategy as a universal first-aid treatment of three different typical snake bites, ACs Biomaterials science &Engineering,2019.(影响因子4.511,二区)

42. jianjian Deng, jing Ye, Yonglei Zhao, Yanglong Zhu, Tianlong Wu, Chong Zhang, Lina Dong, Huan Ouyang, Xigao cheng*Xiaolei Wang*. ZnO and Hydroxyapatite-Modified Magnesium lmplant with a Broad Spectrum of Antilbacterial Properties and aUnique Minimally Invasive Defined Degrading Capability. ACs Biomaterials Science & Engineering, 2019,5 (9), 4285-4292. (影响因子4.511,二区)

43. Mingzhuo Liu, Huiging Zhang, Xiangwei Song, Chaochao Wei, Fen Yu, Chen Li, Fanrong Ai, Guanghua Guo* and XiaoleiWang*, NaCl: for the safer in vivo use of antibacterial silver based nanoparticles, int Nanomedicine, 2018, 13, 1737-1748.(影因子4.471,二区)

44. Yulian Pang, Chaochao Wei, Ruolei li, Yue Wu, Wei Liu, Feifei Wang, Xu Zhang, Xiaolei Wang*. photothermal conversionhydrogel based mini-eye patch for relieving dry eye with long-term use of the light-emiting screen, international Joumnal ofNanomedicine,2019,14,5125-5133.(影响因子4.471,二区)

45. Chaochao Wei, Liu Yu, Xue Tian, Ruolei Li, Wanging Tong, Shuhua Wang, Hongbo Xin, Ping Hu, Xiaolei Wang*. A newglioblastoma targeting therapy concept by using square shaped Janus drug carrier assisted with 3D printed external magneticwearables, Particle & Particle Systems Characterization, 2019,36(3),1800384.(影响因子4.194,二区)

2、专利:

1.杨秀荣(导师为第一作者)、王小磊、朱慧 一种生物吸附剂及其制备方法与应用,2012111,中国,ZL 201210007971.X

2.杨秀荣(导师为第一作者)、王小磊、朱慧 一种生物抗菌剂及其制备方法与应用,2012517日,中国,ZL 201210154125.0

3.朱慧、杨秀荣、王小磊 一种氮掺杂多孔碳材料及其制备方法,2012228日,中国,ZL 201210048084.7

4.朱慧、杨秀荣、王小磊 一种氨掺杂碳材料的制备方法及其应用,2012111日,中国,ZL 102923688B

5.杨秀荣、杨文、杨帆、王小磊、杨成 一种纳米粒子碳纳米管复合物催化剂的制备方法,2008723日,中国,CN 200710307580.9

6.王小磊、辛洪波、余芬、薛超文、史晓彤 一种纳米抗菌防噪耳塞的制备方法,201482日,中国,CN 201410377655.0

7.王小磊、薛超文、商倩楠、胡淇芃、郭菲、张慧庆、史晓彤 一种用于建立老鼠烧伤模型的装置,20151210日,中国,ZL205234687U

8.王小磊、辛洪波、史晓彤、薛超文、项卓、宋相位 一种含纳米氧化亚铜的可见光激发抗菌涂层的制备方法,201618日,中国,CN8.201610009061.3

9.王小磊、辛洪波、董丽娜、刘春镯、余芬、史晓彤、刘苗星 一种用于空气过滤的碳气凝胶的制备方法,2016129日,中国,CN201610060434.X

10.王小磊、辛洪波、项卓 一种用于触摸屏表面的抗菌水凝胶的制备方法,2016819日,中国,ZL 201610689027.5

11.王小磊、陈丽名、张翠翠 一种免血样肿瘤早期监测的方法,20180730日,中国,CN 201810851556.X

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